Evidence supporting the use of: Alstonia macrophylla
For the health condition: Infection

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Alstonia macrophylla, commonly known as the devil tree or "Saptaparni," has a long history of use in traditional medicine systems across South and Southeast Asia. In traditional Ayurveda and local folk practices, its bark and leaves have been employed to manage various infectious conditions such as fevers, malaria, and gastrointestinal disturbances, many of which are presumed to have infectious origins. The use is primarily based on its perceived antipyretic, antimicrobial, and tonic properties.

Scientific studies on Alstonia macrophylla are limited. Some preliminary in vitro research has demonstrated that extracts from the plant possess mild antibacterial and antifungal activity against a range of pathogens. For example, methanolic and ethanolic extracts have shown inhibitory effects against Staphylococcus aureus and Escherichia coli in laboratory settings. However, these results are preliminary, typically conducted in petri dishes rather than in living organisms, and clinical evidence in humans is lacking. There are no large-scale or well-controlled clinical trials verifying its efficacy or safety for treating infections in humans.

In summary, while Alstonia macrophylla is traditionally used to support or treat infections, scientific validation remains weak and mostly preclinical. The evidence base is therefore rated as moderate for tradition but low for scientific support.

More about Alstonia macrophylla
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Products containing Alstonia macrophylla

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