Evidence supporting the use of: American Wormseed
For the health condition: Infection
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
American Wormseed (Dysphania ambrosioides, formerly Chenopodium ambrosioides) has a long history of use in traditional medicine, especially in the Americas, for various ailments including infections and parasitic infestations. In folk medicine, wormseed was commonly employed as an anthelmintic (to expel intestinal worms), but it was also sometimes used for respiratory and gastrointestinal complaints, which may have been associated with infections or inflammation. The traditional rationale for its use against infections likely stems from its perceived purifying and cleansing properties. However, modern scientific research has not provided robust evidence to validate its efficacy as an antimicrobial or anti-infective agent in humans. Some in vitro studies have shown that extracts of wormseed may possess limited antibacterial or antifungal activity, but these findings are preliminary, not well standardized, and have not led to clinical recommendations. The plant contains compounds such as ascaridole, which are toxic at higher doses and limit its safe use. Therefore, while American Wormseed's application for infection is primarily rooted in tradition, there is minimal scientific support for this specific use, and it is not widely recommended in modern herbal pharmacopoeias for infection treatment.
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