Evidence supporting the use of: Bacillus (mixed)
For the health condition: Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacillus species, particularly Bacillus subtilis and Bacillus clausii, are used as probiotics and have been investigated for their role in supporting or treating infections, primarily gastrointestinal infections. Several studies and clinical trials have evaluated their effectiveness in managing conditions like antibiotic-associated diarrhea, Clostridioides difficile infection, and other forms of gut dysbiosis. The mechanism of action is thought to involve competitive exclusion of pathogenic bacteria, modulation of host immune responses, and production of antimicrobial compounds such as bacteriocins. For example, Bacillus clausii has been shown in randomized controlled trials to reduce the duration and severity of diarrhea in both children and adults, especially when used alongside conventional antibiotic therapy.

However, while there is supportive scientific evidence for their use in the prevention and adjunctive treatment of some gut infections, the overall quality and quantity of evidence is moderate, and benefits are generally modest. There is less evidence supporting their use in treating infections outside the gastrointestinal tract. Most guidelines do not recommend Bacillus-based probiotics as a primary therapy for infection but recognize their potential as supportive agents. Safety profiles are generally good, though rare cases of bacteremia have been reported, particularly in immunocompromised patients. Overall, the use of mixed Bacillus species for infection is supported by scientific evidence, but that evidence is not robust or universally accepted, warranting a moderate evidence rating.

More about Bacillus (mixed)
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lactococcus lactis
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lactoperoxidase
lauric acid
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monolaurin
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myrrh
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oriental arborvitae
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eucalyptus
polyporus
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Bifidobacterium
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Products containing Bacillus (mixed)

We currently have no products on Vitabase that contain this ingredient.