Evidence supporting the use of: Reishi mushroom
For the health condition: Infection

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has a long history of use in traditional Chinese medicine (TCM) for supporting the immune system and helping the body resist various infections. In TCM, reishi is considered a "superior herb" known to promote longevity and overall vitality, and it has been used to "strengthen qi," or life force, and support the body's resistance to pathogens. While modern scientific studies have explored reishi’s effects on the immune system, most research focuses on its immunomodulatory properties rather than direct anti-infective effects. Some laboratory and animal studies suggest that reishi extracts may stimulate immune cell activity (such as macrophages and natural killer cells) and enhance the production of cytokines, which could theoretically bolster the body's defense against infections. However, high-quality clinical trials in humans confirming its effectiveness specifically for treating or preventing infections are limited or inconclusive. Therefore, while the traditional use of reishi for supporting infection resilience is well-documented, scientific validation remains preliminary. For now, its reputation in this context relies more on traditional and historical use than on robust clinical evidence.

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