Evidence supporting the use of: Celandine
For the health condition: Infection (bacterial)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Celandine (Chelidonium majus) has a long history of use in traditional herbal medicine, particularly in Europe and parts of Asia. Historically, it has been applied topically to treat skin infections, warts, and other skin maladies, largely due to its bright yellow sap, which was believed to have cleansing and antimicrobial properties. Some folk practices also included internal use for infections, though this was less common due to the plant’s known toxicity.
From a scientific standpoint, laboratory studies have identified certain alkaloids in celandine, such as chelidonine and sanguinarine, that exhibit antimicrobial activity against some bacterial strains in vitro. However, these findings are preliminary and do not robustly translate to clinical efficacy in humans. No substantial clinical trials or regulated studies have demonstrated celandine’s safety or effectiveness for treating bacterial infections in humans. Additionally, there are concerns regarding the safety of celandine, particularly its hepatotoxic potential.
Overall, while celandine has traditional use for treating infections, the scientific support for this application is limited to in vitro studies and does not yet justify its use for bacterial infections in evidence-based medicine. As such, its use for infections remains rooted in traditional practices rather than modern scientific validation.
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bearberry
myrobalan
berberine
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betel
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bifidobacterium lactis
bifidobacterium longum
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black pepper
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caprylic acid
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cat's claw
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turmeric
curcumin
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diallyl disulfide (DADS)
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elderberry
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goldenseal
heartwood
immunoglobin G
iodine
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lactobacillus brevis
lactobacillus crispatus
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
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