Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Glucose oxidase is an enzyme widely recognized for its antimicrobial properties, especially in the context of wound care and infection management. Its use is primarily supported by scientific evidence stemming from its natural occurrence in honey, where it catalyzes the conversion of glucose to gluconic acid and hydrogen peroxide. The hydrogen peroxide produced has well-established antibacterial properties. Medical-grade honey products, such as Manuka honey, leverage glucose oxidase activity to generate low, sustained levels of hydrogen peroxide, contributing to their effectiveness in inhibiting the growth of a range of pathogenic bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa, common culprits in infected wounds.

Several in vitro and in vivo studies have demonstrated the efficacy of glucose oxidase-containing formulations in reducing microbial loads and supporting wound healing. Additionally, research has explored the incorporation of glucose oxidase into wound dressings and topical preparations, showing promising results for reducing bacterial colonization and biofilm formation. However, while the biochemical mechanism and laboratory studies are robust, large-scale clinical trials directly evaluating glucose oxidase alone as a treatment for infection are relatively limited, and most clinical use is as part of composite products like honey or engineered dressings.

In summary, there is scientific validation for the antimicrobial role of glucose oxidase, particularly in wound care, but the clinical evidence base is moderate and largely associated with combination therapies rather than the purified enzyme alone.

More about Glucose Oxidase
More about Infection (bacterial)

Other ingredients used for Infection (bacterial)

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alpha-pinene
annatto
bacillus clausii
bacillus subtilis
barberry
bayberry
bearberry
myrobalan
berberine
Beta-Glucan
betel
bifidobacterium bifidum
bifidobacterium lactis
bifidobacterium longum
bisabolol
black cumin
black pepper
black walnut
burdock
caprylic acid
cassia bark
cat's claw
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turmeric
curcumin
cuspidatum root
diallyl disulfide (DADS)
echinacea purpurea
elderberry
ginger
goldenseal
heartwood
immunoglobin G
iodine
L12-myoviridae
lactobacillus brevis
lactobacillus crispatus
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
licorice root
mangosteen
methenamine
monolaurin
moringa
n-acetyl-cysteine (NAC)
purified silver
saccharomyces boulardii
schizonepeta
shiitake mushroom
streptococcus thermophilus
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vitamin C
vitamin D
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xylitol
zinc
bentonite
sarsaparilla
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pistacia integerrima gall
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caesalpinia crista
rubia cordifolia
swertia
pau d'arco
myrrh
oriental arborvitae
eucalyptus
white oak
Abies spectabilis
geranium
red root
sea salt
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Alcohol
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benzyl isothiocyanate
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Other health conditions supported by Glucose Oxidase

Cuts
Infection (bacterial)
Wounds and Sores

Products containing Glucose Oxidase

We currently have no products on Vitabase that contain this ingredient.