Evidence supporting the use of: Hydrogen peroxide
For the health condition: Infection (bacterial)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Hydrogen peroxide (H2O2) has a long history of use as an antiseptic for minor wounds and bacterial infections on the skin. Its antimicrobial properties are well documented: hydrogen peroxide works by releasing oxygen free radicals, which oxidize and damage cell components of bacteria, leading to their destruction. This mechanism has been demonstrated in both in vitro and in vivo studies, showing broad-spectrum activity against bacteria, viruses, and fungi.

Clinically, hydrogen peroxide is most commonly used as a topical agent for cleaning wounds and preventing superficial infections. Some clinical guidelines recommend its use for initial wound cleansing due to its ability to mechanically remove debris and reduce bacterial load. However, its use is generally limited to superficial wounds, as higher concentrations or prolonged exposure can damage healthy tissue and impede healing. For deeper or chronic wounds, or for systemic infections, hydrogen peroxide is not recommended due to the risk of tissue toxicity and lack of evidence for benefit.

Overall, while hydrogen peroxide’s use is supported by scientific evidence for minor, superficial bacterial infections and wound cleansing, its efficacy is moderate and it is not recommended for deeper or more serious infections. The evidence is strongest for its antimicrobial action in vitro and in minor wound care, but less robust for clinical outcomes compared to other antiseptics.

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Products containing Hydrogen peroxide

We currently have no products on Vitabase that contain this ingredient.