Evidence supporting the use of: Isothiocyanates
For the health condition: Infection (bacterial)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Isothiocyanates, a class of compounds found in cruciferous vegetables such as broccoli, cabbage, and mustard, have demonstrated antibacterial activity in several laboratory studies. The most studied isothiocyanate, sulforaphane, and others like allyl-isothiocyanate, have shown the ability to inhibit the growth of various pathogenic bacteria, including Helicobacter pylori, Escherichia coli, and Staphylococcus aureus. These effects are primarily observed in vitro (test tube studies), where isothiocyanates disrupt bacterial cell walls, interfere with bacterial enzymes, and inhibit biofilm formation. Animal studies have also indicated some efficacy in reducing bacterial load and infection severity.
However, evidence in humans is limited. While some small clinical studies suggest that dietary intake of cruciferous vegetables may help reduce H. pylori colonization, robust clinical evidence for the use of isolated isothiocyanates as a treatment for bacterial infections is lacking. There is ongoing research exploring their potential as adjuncts to traditional antibiotics or as templates for new antimicrobial agents. Overall, while there is promising laboratory and some preliminary clinical evidence, more high-quality human studies are needed to fully validate their efficacy in treating bacterial infections.
Other ingredients used for Infection (bacterial)
2'-FucosyllactoseAjoene
Allspice
alpha-pinene
annatto
bacillus clausii
bacillus subtilis
barberry
bayberry
bearberry
Myrobalan
berberine
beta-glucan
betel
Bifidobacterium bifidum
Bifidobacterium lactis
Bifidobacterium longum
bisabolol
black cumin
black pepper
black walnut
burdock
caprylic acid
cassia bark
cat's claw
Coptis chinensis
turmeric
curcumin
cuspidatum root
diallyl disulfide (DADS)
echinacea purpurea
elderberry
ginger
goldenseal
heartwood
immunoglobin G
iodine
L12-Myoviridae
Lactobacillus brevis
Lactobacillus crispatus
Lactobacillus gasseri
Lactobacillus lactis
Lactobacillus paracasei
lactiplantibacillus plantarum
Lactobacillus salivarius
Lactoferrin
Lactoperoxidase
lauric acid
licorice root
mangosteen
Methenamine
Monolaurin
Moringa
N-acetyl-cysteine (NAC)
purified silver
Saccharomyces boulardii
schizonepeta
shiitake mushroom
streptococcus thermophilus
T4D-Myoviridae
vitamin C
vitamin D
Wasabi
Xylitol
Zinc
bentonite
sarsaparilla
Yellow root
pistacia integerrima gall
blackboard tree
Caesalpinia crista
Rubia cordifolia
Swertia
pau d'arco
Myrrh
oriental arborvitae
eucalyptus
White oak
Abies spectabilis
geranium
red root
sea salt
15,16-Dihydrotanshinone I
3-Phenyllactic Acid
Alcohol
avens
Agarikon Mushroom
apple cider vinegar
Agastache
alpha-terpineol
Acacia
Agave
Allicin
Achyranthes
anamu
Abrus
Alchornea
Asarum heterotropoides
aucubin
andrographolide
Asam gelugor
Andrographis
Alstonia scholaris
Allyl sulfide
Acemannan
Allyl isothiocyanate
Alliin
Abuta
Allium tuberosum
Amor seco
Alantolactone
bee propolis
Bifidobacterium
babchi
Baphicacanthus cusia
Blepharis
Baccharis dracunculifolia
Berberis (unspecified)
Brazilian peppertree
Basidiomycota
Brevibacillus brevis
Bauhinia
Bacillus licheniformis
Baccharoides anthelmintica
Backhousia citriodora
Bifidobacterium animalis
back nightshade
bacteria
Bacillus
benzyl isothiocyanate
Bassia scoparia
Belamcanda
Bergenia
Clerodendrum trichotomum
coconut oil
coriolus mushroom
Combretum quadrangulare
carvacrol
cinquefoil
Cymbidium goeringii
cajuput
celandine
Centipeda
Cistus
Campsiandra angustifolia
chirata
Chaenomeles lagenaria
calamus
Coin-leaf desmodium
Ceanothus integerrimus
cosmos
Cynodon dactylon
Chiococca alba
cocklebur
copaiba oil
Celosia
dehydroabietic acid
divi-divi
dialyzable leukocyte extract
Dichrostachys glomerata
Echinacea
elephant\'s head
Euphorbia
elemi
Embelia
eugenol
fucoidan
Flueggea suffruticosa
Fomes fomentarius
fang-feng
Ficus religiosa
geraniol
glyceryl monolaurate
glyceryl caprylate caprate
Globulins
Graviola
galangin
Gallesia
golden shower tree
Guazuma ulmifolia
Hygrophila
Houttuynia
Hydrocolloid
Humic acid
Horsemint
Immunoglobulin G
Isoalantolactone
Indian coraltree
isothiocyanates
Kigelia africana
Kachnar
Kochia
knotgrass
Kefiran
lime
Lactobacillus kefiri
Lactococcus rhamnosus
lichen
Lophira lanceolata
Lapachol
lactic acid
Lactococcus casei
lysozyme
Leptadenia
Lantana camara
Leptospermum scoparium
Lactobacillus
liverwort
L. lactis
Lysimachia
Labdanum
Lauric arginate
Mezoneuron benthamianum
Mountain horopito
Marsh Tea
Malva sylvestris
Matapalo Tree
mangostin
Mahonia
Microtea debilis
Milkweed
Mondo grass
mangostanol
mannose
manzanita
Macaranga indica
Naphthoquinones
Nisin
Nasturtium
Osha
Orris
Oldenlandia diffusa
Phellodendron
purple Tephrosia
Premna
Phragmites
Pluchea
Paenibacillus polymyxa
Pepper Bark Tree
phlorotannins
probiotics
Pediococcus acidilactici
Piper retrofractum
Pentatropis capensis
Pareira
Plumbago zeylanica
Peroxidase
Plectranthus amboinicus
Quebracho
Quisqualis
Rubia yunnanensis
Rosa laevigata
Spilanthes
Spanish Needle
Streptomyces
Streptomyces cellulosae
Shikonin
Self-Heal
Stemona
Siphoviridae
Sanguisorba
Streptomyces fradiae
Sesquiterpenic Acid
Streptococcus salivarius
Sarcandra glabra
Savory
Streptomyces griseoflavus
Simaruba
Sulfated polysaccharide
Storax
Smoketree
Sword Bean
Tannins
Terpinen-4-ol
Thuja
Thymol
Trametes
Thiosulfinate
Teri Pod
Umckaloabo
Umckalin
Vinegar
Verbascoside
Waltheria ovata
Xanthorrhizol
Zingerone
Other health conditions supported by isothiocyanates
Cancer (natural therapy for)Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Diabetes
Infection (bacterial)
Inflammation
Liver Detoxification
Ulcers