Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus paracasei is a probiotic bacterium that has been studied for its potential to support the body in managing or preventing certain bacterial infections. The scientific rationale behind its use is based on its ability to compete with pathogenic bacteria for adhesion sites on mucosal surfaces, produce antimicrobial substances (such as organic acids and bacteriocins), and modulate the host immune response to enhance protection against pathogens.

There is moderate evidence from in vitro studies and some animal models showing that L. paracasei can inhibit the growth of a variety of pathogenic bacteria, including Escherichia coli, Salmonella spp., and Staphylococcus aureus. Human studies are more limited but suggest some benefit in reducing the incidence or severity of infections such as diarrhea (including antibiotic-associated and infectious diarrhea) and respiratory tract infections, particularly in children and vulnerable populations. For example, clinical trials have indicated that L. paracasei supplementation may reduce the duration and severity of acute infectious diarrhea and help restore healthy gut microbiota after antibiotic use.

However, the overall quality and quantity of clinical evidence remain modest, and the effectiveness can be strain-specific. The evidence is not strong enough to recommend L. paracasei as a primary treatment for established bacterial infections, but it may have adjunctive or preventive roles. As such, it receives a moderate evidence rating (2 out of 5), reflecting promising results but a need for more robust clinical trials to confirm efficacy and clarify mechanisms.

More about lactobacillus paracasei
More about Infection (bacterial)

Other ingredients used for Infection (bacterial)

Other health conditions supported by lactobacillus paracasei

Products containing lactobacillus paracasei

Vitabase 7 Day Colon Cleanse
Integrative Therapeutics Enterogenic Intensive 100
Thorne FloraSport 20B NSF
Douglas Laboratories Multi-Probiotic ® 40 Billion
Douglas Laboratories Multi-Probiotic ® 40 Billion
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Designs For Health ProbioMed™ 100
Designs For Health ProbioMed™ 250
Designs For Health ProbioMed™ 50
Designs For Health ProbioMed Kids
Designs For Health ProbioMed™ Women
Vitabase Probiotic Blend
Metagenics UltraFlora BiomePro Probiotic
Metagenics UltraFlora Immune Booster Probiotic
Metagenics UltraFlora Restore Probiotic