Evidence supporting the use of: Saccharomyces
For the health condition: Infection (bacterial)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Saccharomyces, particularly the species Saccharomyces boulardii, has scientific support for its use in helping manage certain bacterial infections, especially those affecting the gastrointestinal tract. S. boulardii is a probiotic yeast that has been studied for its role in preventing and treating antibiotic-associated diarrhea, including that caused by Clostridioides difficile (formerly Clostridium difficile). Clinical trials and meta-analyses indicate that S. boulardii can reduce the incidence and duration of diarrhea in both adults and children taking antibiotics. Additionally, some studies suggest it may help prevent recurrence of C. difficile infection when used alongside standard antibiotic therapy.
The proposed mechanisms for these benefits include restoration of the normal gut microbiota, secretion of factors that neutralize bacterial toxins, competitive exclusion of pathogens, and modulation of local immune responses. It is important to note that the strongest evidence is for gastrointestinal conditions; there is limited or no evidence supporting the use of Saccharomyces for systemic or non-GI bacterial infections. The overall quality of evidence is moderate, with systematic reviews generally supporting its use in specific, well-defined scenarios related to GI infections, but not as a broad-spectrum antibacterial treatment.
In summary, Saccharomyces (mainly S. boulardii) is scientifically validated as a supportive therapy for certain bacterial GI infections, particularly antibiotic-associated and C. difficile-related diarrhea, with evidence level around 3/5.
Other ingredients used for Infection (bacterial)
2'-Fucosyllactoseajoene
allspice
alpha-pinene
annatto
bacillus clausii
bacillus subtilis
barberry
bayberry
bearberry
myrobalan
berberine
Beta-Glucan
betel
bifidobacterium bifidum
bifidobacterium lactis
bifidobacterium longum
bisabolol
black cumin
black pepper
black walnut
burdock
caprylic acid
cassia bark
cat's claw
Coptis chinensis
turmeric
curcumin
cuspidatum root
diallyl disulfide (DADS)
echinacea purpurea
elderberry
ginger
goldenseal
heartwood
immunoglobin G
iodine
L12-myoviridae
lactobacillus brevis
lactobacillus crispatus
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
LH01-myoviridae
licorice root
LL12-myoviridae
LL5-siphoviridae
mangosteen
methenamine
monolaurin
moringa
n-acetyl-cysteine (NAC)
purified silver
saccharomyces boulardii
schizonepeta
shiitake mushroom
streptococcus thermophilus
T4D-myoviridae
vitamin C
vitamin D
wasabia japonica
xylitol
zinc
bentonite
sarsaparilla
yellow root
pistacia integerrima gall
blackboard tree
caesalpinia crista
rubia cordifolia
swertia
pau d'arco
myrrh
oriental arborvitae
eucalyptus
white oak
abies spectabilis
geranium
sea salt
15,16-Dihydrotanshinone I
3-Phenyllactic Acid
Alcohol
Avens
Agarikon Mushroom
Apple Cider Vinegar
Agastache
Alpha-terpineol
acacia
Agave
Allicin
Achyranthes
Anamu
Abrus
Alchornea
Asarum heterotropoides
Aucubin
Andrographolide
Asam gelugor
Andrographis
Alsonia scholaris
Allyl Sulfide
Acemannan
allyl isothiocyanate
Alliin
Abuta
Allium tuberosum
Amor seco
Alantolactone
Bee Propolis
Bifidobacterium
Babchi
Baphicacanthus cusia
Blepharis
Baccharis dracunculifolia
Berberis (unspecified)
Brazillian peppertree
Basidiomycota
Brevibacillus brevis
Bauhinia
Bacillus licheniformis
Baccharoides anthelmintica
Backhousia citriodora
Bifidobacterium animalis
Black Nightshade
Bacteria
Bacillus
benzyl isothiocyanate
Bassia scoparia
Belamcanda
Bergenia
Clerodendrum trichotomum
coconut oil
Coriolus mushroom
Combretum quadrangulare
Carvacrol
Cinquefoil
Cymbidium goeringii
Cajuput
Celandine
Centipeda
Cistus
Campsiandra angustifolia
Chirata
Chaenomeles lagenaria
Calamus
Coin-leaf desmodium
Ceanothus integerrimus
Cosmos
Cynodon dactylon
Chiococca alba
Cocklebur
Copaiba Oil
Celosia
Dehydroabietic acid
DIVI-DIVI
Dialyzable Leukocyte Extract
Dichrostachys glomerata
Echinacea
Elephant's Head
Euphorbia
Elemi
Embelia
Eugenol
Vinegar
Other health conditions supported by Saccharomyces
Antibiotics (alternatives to)Antibiotics (side effects of)
Cancer Treatment (reducing side effects)
Diarrhea
Infection
Infection (bacterial)
Inflammation
Irritable Bowel Syndrome