Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Siphoviridae is a family of bacteriophages (viruses that infect bacteria), and their use in treating bacterial infections is supported by a growing body of scientific evidence. Bacteriophage therapy, including the use of Siphoviridae phages, has been explored for over a century, but recent advances in molecular biology and genomics have revitalized interest in their application as alternatives or adjuncts to antibiotics, especially in the context of antibiotic-resistant bacterial infections.

Numerous in vitro and in vivo studies have demonstrated the ability of Siphoviridae phages to specifically target and lyse pathogenic bacteria such as Staphylococcus aureus and Escherichia coli. Several case reports and small clinical studies have reported successful treatment of multidrug-resistant infections using phage preparations containing Siphoviridae members. The specificity of these phages reduces the risk of disrupting normal microbiota compared to broad-spectrum antibiotics.

While large-scale randomized controlled trials are still limited, the scientific foundation for the use of Siphoviridae in phage therapy is strong, supported by mechanistic studies, compassionate-use cases, and early-phase clinical work. This places the evidence at a moderate-to-high level (4/5), pending further clinical confirmation. Regulatory, manufacturing, and safety considerations remain, but the scientific rationale for using Siphoviridae against bacterial infections is well-established and growing stronger with ongoing research.

More about Siphoviridae
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Other ingredients used for Infection (bacterial)

2'-Fucosyllactose
Ajoene
Allspice
alpha-pinene
annatto
bacillus clausii
bacillus subtilis
barberry
bayberry
bearberry
myrobalan
berberine
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betel
bifidobacterium bifidum
bifidobacterium lactis
bifidobacterium longum
bisabolol
black cumin
black pepper
black walnut
burdock
caprylic acid
cassia bark
cat's claw
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turmeric
curcumin
cuspidatum root
diallyl disulfide (DADS)
echinacea purpurea
elderberry
ginger
goldenseal
heartwood
immunoglobin G
iodine
L12-myoviridae
lactobacillus brevis
lactobacillus crispatus
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus salivarius
lactoferrin
lactoperoxidase
lauric acid
licorice root
mangosteen
methenamine
monolaurin
moringa
n-acetyl-cysteine (NAC)
purified silver
saccharomyces boulardii
schizonepeta
shiitake mushroom
streptococcus thermophilus
T4D-myoviridae
vitamin C
vitamin D
Wasabi
xylitol
zinc
bentonite
sarsaparilla
yellow root
pistacia integerrima gall
blackboard tree
caesalpinia crista
rubia cordifolia
swertia
pau d'arco
myrrh
oriental arborvitae
eucalyptus
white oak
Abies spectabilis
geranium
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sea salt
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Other health conditions supported by Siphoviridae

Infection
Infection (bacterial)
Staph Infections

Products containing Siphoviridae

We currently have no products on Vitabase that contain this ingredient.