Evidence supporting the use of: Arabinogalactans
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Arabinogalactans are polysaccharides derived primarily from the larch tree (Larix spp.) and are sometimes used as dietary supplements to support immune function. There is limited scientific evidence suggesting that arabinogalactans may have a role in modulating immune responses and potentially supporting resistance to certain infections, including viral infections. Some in vitro and animal studies have shown that arabinogalactans can enhance natural killer (NK) cell activity, stimulate macrophages, and increase the production of cytokines involved in immune defense. A few small clinical trials have investigated their effects on immune parameters and the incidence of upper respiratory tract infections (URTIs), with mixed results. For example, one randomized controlled trial found a reduction in the incidence of cold episodes among healthy adults taking larch arabinogalactan compared to placebo, but the effect size was modest and the study had limitations such as small sample size.

Overall, while there are some early-stage studies and plausible mechanisms for immune support, robust clinical evidence for the use of arabinogalactans specifically in the prevention or treatment of viral infections in humans is lacking. Most authoritative bodies do not endorse its use for this purpose, and further well-designed clinical trials are needed to determine its true efficacy and relevance. Thus, the evidence is currently rated as low (2 out of 5).

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Products containing Arabinogalactans

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