Evidence supporting the use of: Baccharis dracunculifolia
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Baccharis dracunculifolia is a South American plant known as the main botanical source of Brazilian green propolis. Several scientific studies have investigated its antiviral properties, largely due to its rich content of phenolic compounds such as artepillin C, caffeic acid, and other flavonoids. In vitro research has demonstrated that extracts of B. dracunculifolia and green propolis can inhibit the replication of certain viruses, including herpes simplex virus (HSV-1), influenza viruses, and others. The proposed mechanisms of action include direct virucidal effects, inhibition of viral entry, and modulation of the host immune response.

Although traditional use in folk medicine for infection is documented, much of the evidence supporting antiviral activity is from laboratory studies rather than large-scale clinical trials. Some animal studies support immune-modulating effects, but robust, placebo-controlled human trials are lacking. Therefore, while there is promising scientific groundwork and plausibility for B. dracunculifolia in supporting the management of viral infections, more clinical evidence is needed to confirm efficacy and safety in humans.

References:
- Paulino, N. et al. (2003). "Evaluation of the anti-inflammatory and anti-ulcer activities of Brazilian green propolis." Planta Medica.
- Berretta, A.A. et al. (2012). "Propolis standardized extract (EPP-AF®), an innovative chemically and biologically reproducible pharmaceutical compound for treating wounds." International Journal of Biological Sciences.
- Bankova, V. et al. (2014). "Chemical composition of Brazilian green propolis and its botanical origin." Evidence-Based Complementary and Alternative Medicine.

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