Evidence supporting the use of: Beta-glucan
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Beta-glucan is a polysaccharide found in the cell walls of cereals, bacteria, and fungi. Its use to support the immune system and help combat viral infections is primarily justified by scientific evidence, though this evidence remains preliminary. Beta-glucans are recognized as biological response modifiers that can enhance innate immune responses. They stimulate macrophages, neutrophils, and natural killer (NK) cells, which play roles in the body’s defense against pathogens, including viruses.

Several in vitro and animal studies have shown that beta-glucans can increase resistance to viral infections by boosting immune cell activity and modulating cytokine production. For example, animal research has demonstrated enhanced protection against influenza and herpes simplex virus following beta-glucan supplementation. Some small-scale human studies suggest beta-glucan may reduce the incidence or severity of upper respiratory tract infections, implying potential antiviral benefits. However, robust, large-scale, placebo-controlled clinical trials specifically targeting viral infections in humans are limited.

Overall, while the immunomodulatory effects of beta-glucan are well-documented, evidence supporting its use in the treatment or prevention of viral infections is not conclusive. The evidence base is growing but remains at an early stage, justifying a moderate rating. More research is needed to confirm clinical effectiveness and determine optimal dosing for antiviral support.

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