Evidence supporting the use of: Galangin
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Galangin is a flavonoid compound found primarily in the rhizomes of Alpinia officinarum (lesser galangal) and propolis. It has been investigated for a range of pharmacological activities, including antiviral effects. Several in vitro studies have demonstrated that galangin can inhibit the replication of certain viruses, such as herpes simplex virus type 1 (HSV-1), hepatitis B virus (HBV), and influenza A virus. The proposed mechanisms include inhibition of viral DNA synthesis, interference with viral entry or attachment, and modulation of host immune responses. For example, a 2015 study published in Phytotherapy Research found that galangin suppressed HSV-1 replication in cell cultures, while another study in the Journal of Ethnopharmacology showed inhibition of HBV antigens in HepG2 cells.

Despite these promising in vitro findings, there is a lack of robust in vivo or clinical evidence supporting the efficacy of galangin for treating viral infections in humans. No large-scale clinical trials have been published to date. Thus, while scientific research provides preliminary support for the antiviral potential of galangin, the evidence base is limited and primarily preclinical. More rigorous studies, including human trials, are needed to determine its safety and effectiveness for this indication.

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Products containing Galangin

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