Evidence supporting the use of: Globulins
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Globulins, specifically immunoglobulins (antibodies), are scientifically validated for use in the prevention and treatment of certain viral infections. Immunoglobulin therapy involves administering pooled antibodies from human plasma to confer passive immunity. This approach is especially important for individuals with compromised immune systems or those exposed to specific viral pathogens. For example, intravenous immunoglobulin (IVIG) is used to treat or prevent infections such as hepatitis B, rabies, measles, and varicella-zoster in situations where vaccination is not possible or effective, or following exposure. The mechanism involves providing immediate, though temporary, immunity by supplying antibodies that neutralize viruses and facilitate their clearance from the body. Robust evidence supports the efficacy of immunoglobulin preparations in reducing severity or preventing the onset of viral diseases when given appropriately. Clinical guidelines recommend their use in post-exposure prophylaxis and in treating certain immunodeficiencies. However, it is important to note that immunoglobulins are not a universal antiviral therapy; their effectiveness is limited to viruses for which the pooled antibodies contain sufficient titers. Randomized controlled trials and decades of clinical use have established safety and benefit in these settings, though the degree of benefit depends on timing, dose, and the specific viral threat involved. Thus, globulins (as immunoglobulins) are a scientifically validated, targeted therapy for viral infections in defined circumstances.

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Products containing Globulins

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