Evidence supporting the use of: Hypericin
For the health condition: Infection (viral)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hypericin is a naturally occurring compound found in the plant Hypericum perforatum (St. John's Wort). Its use in viral infections is primarily supported by laboratory and preclinical studies rather than robust clinical evidence. In vitro (test tube) studies have demonstrated that hypericin possesses antiviral activity against a range of viruses, including enveloped viruses such as HIV, herpes simplex virus, and some flaviviruses. The proposed mechanism involves hypericin's ability to generate reactive oxygen species upon exposure to light, which can inactivate viral particles and disrupt viral replication.

Despite these promising laboratory results, clinical trials in humans are scarce and largely inconclusive. There is not enough evidence from well-conducted human studies to support the routine use of hypericin or St. John's Wort extracts for the treatment or prevention of viral infections. Most clinical research on St. John's Wort focuses on its antidepressant properties rather than its antiviral effects.

In summary, while there is scientific rationale and some preclinical evidence for hypericin's antiviral activity, clinical validation is lacking. The evidence rating is 2, reflecting promising laboratory data but insufficient human data to support its use for viral infections in clinical settings.

More about Hypericin
More about Infection (viral)

Products containing Hypericin

We currently have no products on Vitabase that contain this ingredient.