Evidence supporting the use of: Immunoglobulins
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Immunoglobulins (also known as antibodies or immune globulins) are scientifically validated for use in the treatment and prevention of certain viral infections. Immunoglobulin preparations, particularly intravenous immunoglobulin (IVIG), contain pooled antibodies from the plasma of healthy donors. These antibodies can provide passive immunity to individuals who are immunocompromised or at risk of severe disease. Their use is well-documented in the prevention of infections such as hepatitis B, rabies, measles, and varicella-zoster, especially in cases of exposure when vaccination is not possible or when immediate immunity is required. For example, hepatitis B immune globulin (HBIG) is administered to newborns of hepatitis B-infected mothers and individuals with high-risk exposure. Similarly, rabies immune globulin is part of post-exposure prophylaxis after potential rabies virus exposure.

IVIG is also used in certain rare viral infections in immunocompromised patients, such as those with primary immunodeficiencies who are unable to mount their own antibody response. Numerous randomized controlled trials and clinical guidelines support the use of immunoglobulins for these indications, and major health organizations (such as the CDC and WHO) recommend their use according to established protocols. Thus, the use of immunoglobulins against viral infection is strongly supported by scientific evidence, though their use is generally specific to particular viruses and clinical contexts rather than as a general antiviral therapy.

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Products containing Immunoglobulins

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