Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Pistacia integerrima galls, also known as "kakra singhi," are widely used in traditional Ayurvedic and Unani medicine for the treatment of respiratory infections, cough, and other related ailments. The traditional use is largely based on ethnobotanical practices, where the galls are believed to possess antimicrobial, antiviral, and anti-inflammatory properties. Ancient texts and folk remedies often recommend them as an ingredient in herbal formulations to relieve respiratory tract infections, especially in children. Scientific research into the antiviral efficacy of Pistacia integerrima galls is limited. Some in vitro studies have demonstrated that extracts from the galls possess broad-spectrum antimicrobial activity, including activity against certain bacteria and fungi, but robust evidence of direct antiviral effects is lacking. A handful of phytochemical analyses reveal the presence of bioactive compounds such as flavonoids, tannins, and phenolics, which may contribute to immune modulation and indirect support during infections. However, high-quality clinical trials or laboratory studies specifically validating antiviral activity in humans are scarce. In summary, the use of Pistacia integerrima gall for viral infections is strongly rooted in traditional medicine, with some preliminary scientific indications of antimicrobial potential. However, the direct scientific validation, especially for viral infections, remains limited, and further research is needed to confirm its efficacy and safety for this specific purpose.

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