Evidence supporting the use of: Polypodium (unspecified)
For the health condition: Infection (viral)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Polypodium species (such as Polypodium leucotomos and Polypodium vulgare) have a history of use in traditional medicine systems, particularly in Central and South America and Europe. While these ferns have mainly been used for skin disorders, respiratory issues, and as general tonics, some traditional sources mention their use for supporting the body's defense against infections, including viral infections. However, there is very limited direct evidence from traditional medical texts or ethnobotanical records specifically citing Polypodium as a remedy for viral infections. Most available references focus on its anti-inflammatory, antioxidant, and immunomodulatory properties, which could be interpreted as supportive for immune health in a general sense. Scientific research on Polypodium extracts has primarily focused on their photoprotective and anti-inflammatory effects, with few studies examining direct antiviral activity. A handful of laboratory studies suggest possible immune-modulating effects, but robust clinical trials on viral infection outcomes are lacking. In summary, the use of Polypodium for viral infections is grounded more in traditional use and theoretical rationale than substantiated by scientific evidence, and the strength of this evidence is weak.

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