Evidence supporting the use of: Polysaccharides
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Polysaccharides, especially those derived from medicinal mushrooms (such as beta-glucans from Lentinula edodes or Ganoderma lucidum), certain seaweeds, and plants like Astragalus membranaceus, have been investigated for their immunomodulatory properties. Scientific research over the past few decades has demonstrated that some polysaccharides can enhance various aspects of the immune response, including activation of macrophages, natural killer (NK) cells, and the stimulation of cytokine production. These mechanisms suggest a potential for supporting the body's defense against viral infections. For example, beta-glucans have shown the ability to stimulate antiviral immunity in vitro and in some animal studies.

However, the clinical evidence in humans remains limited. Most available studies are preclinical (cell or animal models) or small-scale human trials with methodological limitations. There have been some promising results, such as improved immune markers or reduced symptom severity in upper respiratory tract infections, but robust, large-scale clinical trials demonstrating clear antiviral efficacy are lacking. Thus, while there is a scientific rationale and preliminary evidence supporting polysaccharides' immunomodulatory and potential antiviral effects, the overall strength of evidence for their use in treating or preventing viral infections in humans is moderate to low at this time.

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Products containing Polysaccharides

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