Evidence supporting the use of: Protease Inhibitors
For the health condition: Infection (viral)
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Protease inhibitors are a well-established class of antiviral drugs, particularly used in the treatment of infections caused by viruses such as HIV and Hepatitis C virus (HCV). These medications work by blocking the action of viral protease enzymes, which are essential for the maturation and replication of the virus. By inhibiting these enzymes, protease inhibitors prevent the virus from producing infectious viral particles, thereby reducing viral load in the patient's body.
In the context of HIV, protease inhibitors have been a cornerstone of antiretroviral therapy since the mid-1990s. Multiple large-scale, randomized controlled trials and long-term cohort studies have demonstrated their effectiveness in reducing morbidity and mortality associated with HIV/AIDS. Similarly, in HCV, combinations including protease inhibitors have significantly increased cure rates and shortened treatment duration, as shown in numerous clinical studies.
The use of protease inhibitors is supported by extensive scientific validation, including FDA approval for specific indications and inclusion in international treatment guidelines. Their mechanism of action is well-understood at the molecular level, and their clinical benefits are substantiated by decades of research. Thus, their use in treating viral infections like HIV and HCV is highly evidence-based.
Other ingredients used for Infection (viral)
2'-Fucosyllactoseajoene
alpha-pinene
arabinogalactan
barberry
myrobalan
berberine
Beta-Glucan
betel
black cumin
burdock
cassia bark
cat's claw
Coptis chinensis
turmeric
curcumin
cuspidatum root
diallyl disulfide (DADS)
echinacea purpurea
elderberry
ginger
goldenseal
immunoglobin G
iodine
honeysuckle
L12-myoviridae
lactobacillus paracasei
lactoferrin
lactoperoxidase
lauric acid
licorice root
mangosteen
monolaurin
reishi mushroom
selenium
spirulina
sweet wormwood
T4D-myoviridae
turkey tail mushroom
vitamin A
vitamin C
vitamin D
vitamin D3
xylitol
zinc
sarsaparilla
yellow root
boneset
pistacia integerrima gall
swertia
pau d'arco
yerba santa
oriental arborvitae
eucalyptus
abies spectabilis
geranium
Agarikon Mushroom
Apple Cider Vinegar
Agastache
Agave
Anamu
Alchornea
Asarum heterotropoides
AHCC
Aucubin
Andrographolide
Aureobasidium pullulans
Andrographis
Alsonia scholaris
Acemannan
Alkylglycerols
Alliin
Allium tuberosum
Amor seco
Asarum sieboldii
Artepillin C
Bee Propolis
Babchi
Baphicacanthus cusia
Betulinic acid
Blepharis
Baccharis dracunculifolia
Brazillian peppertree
Bauhinia
Baicalin
Belamcanda
Coriolus mushroom
Carvacrol
Cymbidium goeringii
Casticin
Centipeda
Cistus
Campsiandra angustifolia
Calamus
Coin-leaf desmodium
Dialyzable Leukocyte Extract
European Elder
Echinacea
Fernbush
Ivy
Sandalwood
Other health conditions supported by Protease Inhibitors
Acquired Immune Deficiency SyndromeHepatitis
Infection (viral)