Evidence supporting the use of: Simaruba
For the health condition: Infection (viral)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Simaruba (Simarouba amara or Simarouba glauca) has a longstanding history of use in traditional medicine systems in Central and South America and the Caribbean. Traditionally, its bark and leaves have been used as remedies for a variety of infections, including those thought to be caused by viruses, such as dysentery, malaria, and fevers. Ethnobotanical records indicate its application by indigenous peoples for treating gastrointestinal and febrile illnesses, which were often assumed to be of infectious origin. However, scientific studies directly evaluating Simaruba’s efficacy against viral infections are limited. Some in vitro research indicates that quassinoids and other compounds in Simaruba may possess antimicrobial and antiparasitic properties, but robust antiviral activity in animal or human studies has not been conclusively demonstrated. Most of the available evidence remains anecdotal or based on traditional knowledge rather than rigorous clinical trials. In summary, while Simaruba is traditionally used to support or treat infections—including those believed to be viral—there is insufficient scientific validation for its efficacy against viral pathogens. The evidence supporting its use for viral infections is thus primarily traditional, with a low level of scientific support.

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Products containing Simaruba

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