Evidence supporting the use of: Vitamin A (unspecified)
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin A is an essential micronutrient with important roles in immune function, epithelial integrity, and cellular differentiation. Its use in supporting or treating viral infections is primarily supported by scientific evidence in specific contexts, particularly in the prevention and management of severe measles in children. Clinical studies and World Health Organization (WHO) guidelines recommend high-dose vitamin A supplementation for children with measles in regions where vitamin A deficiency is prevalent, as it has been shown to reduce morbidity and mortality. The mechanism is thought to involve vitamin A's role in maintaining mucosal barriers and enhancing immune responses, which can be compromised during vitamin A deficiency, leading to increased susceptibility and severity of infections.

However, outside of measles and populations with known deficiency, the evidence for vitamin A supplementation as a general treatment or preventative measure against viral infections is limited and does not support widespread use. Randomized controlled trials have not consistently shown benefit for other viral infections, and excessive vitamin A intake can be toxic. Thus, the scientific support for vitamin A in treating viral infections is specific and context-dependent, rather than broadly applicable. Its use is justified in populations at risk for deficiency and in certain infections like measles, but routine supplementation for viral infection in well-nourished individuals is not supported by current evidence.

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Products containing Vitamin A (unspecified)

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