Evidence supporting the use of: Cnidium
For the health condition: Infertility

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Cnidium monnieri is a herb commonly used in Traditional Chinese Medicine (TCM) for reproductive health, including the treatment of infertility. In TCM, Cnidium (commonly referenced as "She Chuang Zi") is believed to invigorate the kidney yang, warm the reproductive organs, and stimulate libido. It has been used historically both topically and internally to address male impotence, female infertility, and various dermatological conditions.

While Cnidium’s traditional use for infertility is well-documented in classical Chinese medical texts and persists in modern herbal practice, robust scientific validation for these effects remains limited. Some laboratory and animal studies have explored Cnidium’s active compounds, such as osthole, which may have effects on nitric oxide production and blood flow—mechanisms that could, in theory, support erectile function. However, direct evidence in human clinical trials demonstrating efficacy for either male or female infertility is lacking.

Overall, Cnidium’s reputation for supporting fertility is rooted in traditional medical systems rather than scientific consensus. It continues to be used in herbal formulas for infertility, especially in East Asia, but those considering its use should be aware that high-quality clinical evidence is minimal, and its effectiveness has not been conclusively demonstrated by modern research.

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