Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Massularia acuminata is primarily used in traditional medicine, particularly in West Africa, for supporting male reproductive health and treating infertility. Ethnobotanical surveys report its use as an aphrodisiac and fertility enhancer among local populations, where parts of the plant—especially the stem—are chewed or used in concoctions for this purpose.

Scientific research on Massularia acuminata is limited but growing. A few animal studies have investigated its effects: for example, a study in rats found that extracts of the stem increased serum testosterone levels, testicular weight, and sperm count. The likely mechanism is attributed to the stimulation of androgen production, possibly via bioactive compounds present in the plant. However, these studies are preclinical and do not provide direct evidence for efficacy in humans or for treating infertility in clinical settings.

There are no large-scale, peer-reviewed human trials to conclusively validate its effectiveness for infertility. The existing evidence is preliminary and mainly supports traditional claims rather than providing robust scientific validation. Therefore, while the traditional use is well documented, the scientific evidence is still emerging and not yet sufficient for firm conclusions.

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