Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Stem cell therapy is an emerging scientific approach for treating infertility, particularly in cases where traditional treatments have failed. Research over the past two decades has shown that stem cells have the potential to differentiate into various reproductive cell types, such as sperm and oocytes. Preclinical studies in animal models have demonstrated that transplantation of stem cells (such as mesenchymal stem cells or induced pluripotent stem cells) can restore spermatogenesis and oogenesis, leading to the production of functional gametes. Several early-phase clinical trials in humans have explored the use of stem cells to treat conditions like premature ovarian failure and non-obstructive azoospermia, reporting some promising, albeit preliminary, results in terms of hormone production and limited restoration of fertility functions.

However, the evidence supporting stem cell therapy for infertility is still limited and largely experimental. Most studies are preclinical or at the early clinical trial stage, and there are significant safety and ethical considerations that must be addressed before widespread clinical adoption. As of now, stem cell therapy is not a standard treatment for infertility, but ongoing research may improve its evidence base and safety profile in the future.

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