Relationship: Infertility and vitamin E

Evidence supporting the use of: Vitamin E
For the health condition: Infertility

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Source of validity: Scientific
Rating (out of 5): 2

Vitamin E has been investigated for its potential role in supporting or treating infertility, particularly due to its antioxidant properties. The rationale is that oxidative stress can negatively impact reproductive health in both men and women—damaging sperm DNA, reducing motility, and affecting oocyte quality and endometrial receptivity. Vitamin E, as a lipid-soluble antioxidant, helps neutralize free radicals, potentially protecting reproductive cells from oxidative damage.

Some clinical studies have evaluated vitamin E supplementation in men with idiopathic infertility. Meta-analyses and randomized controlled trials have shown modest improvements in sperm motility and a reduction in sperm DNA fragmentation after vitamin E supplementation, especially when combined with other antioxidants. For example, a 2019 review in Andrologia reported improved sperm parameters and pregnancy rates in some trials, but the overall quality of evidence was low to moderate, and results were inconsistent.

In women, evidence is less robust, with only a few small studies suggesting possible benefits in improving endometrial thickness or IVF outcomes. However, these findings are not consistent, and more large-scale, high-quality trials are needed to confirm efficacy.

In summary, while there is a plausible biological mechanism and some supportive data, the scientific evidence for vitamin E as a treatment for infertility is limited and inconsistent. Current guidelines do not recommend vitamin E as a first-line therapy for infertility, but it may be considered as an adjunct in certain cases, especially in the management of oxidative stress-related infertility.

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Acne
Age Spots
Aging (prevention)
Alzheimer's Disease
Anemia
Arteriosclerosis
Arthritis
Asthma
Autoimmune Disorders
Bites and Stings
Blisters
Boils
Breast Lumps
Breasts (swelling and tenderness)
Bruises (healing)
Cancer Treatment (reducing side effects)
Capillary Weakness
Cardiovascular Disease
Cataracts
Cellulite
Cervical Dysplasia
Chemotherapy (reducing side effects)
Circulation (poor)
Cirrhosis of the Liver
Cold Sores
Dermatitis
Diabetes
Diabetic Retinopathy
Dysmenorrhea
Eczema
Endometriosis
Epilepsy
Eye Problems
Eyesight (poor)
Fatty Liver Disease
Fingernails (weak or brittle)
Free Radical Damage
Frostbite (prevention)
Gingivitis
Hair (loss or thinning)
Hair Care (general)
Heart (weakness)
Hepatitis
Hot Flashes
Infertility
Inflammation
Injuries
Itching
Itching Ears
Lesions
Liver Detoxification
Macular Degeneration
Memory and Brain Function
Menopause
Menorrhagia
Migraine
Nerve Damage
Neuralgia and Neuritis
Peripheral Neuropathy
Psoriasis
Radiation Sickness
Rashes and Hives
Scars / Scar Tissue
Skin (dry and/or flaky)
Skin Care (general)
Stretch Marks
Sunburn
Surgery (healing from)

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Evidence supporting the use of: Vitamin E
For the health condition: Infertility

Table of Contents

Synopsis

Other ingredients used for Infertility

Other health conditions supported by vitamin E

Products containing vitamin E

Health Concerns

Brands

Evidence supporting the use of: Vitamin EFor the health condition: Infertility

Table of Contents

Synopsis

Other ingredients used for Infertility

Other health conditions supported by vitamin E

Products containing vitamin E

Evidence supporting the use of: Vitamin E
For the health condition: Infertility