Evidence supporting the use of: Vitex Agnus-Castus
For the health condition: Infertility

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitex agnus-castus, also known as chaste tree berry, has a long history of traditional use in supporting female reproductive health, including for infertility. Its use dates back to ancient Greece and Rome, where it was believed to influence hormonal balance. The traditional rationale for using Vitex in infertility centers on its reputed ability to regulate the menstrual cycle, particularly in women with luteal phase defects (short second half of the cycle), which can contribute to difficulties in conceiving.

Scientific research on Vitex agnus-castus for infertility is limited and of mixed quality. Some small clinical trials and observational studies suggest that Vitex may help normalize progesterone levels and improve menstrual regularity in women with certain conditions, such as premenstrual syndrome or mild hyperprolactinemia, which can be associated with infertility. However, well-conducted randomized controlled trials specifically evaluating its effectiveness in improving fertility or pregnancy rates are sparse. Most findings remain preliminary, and the precise mechanisms by which Vitex might influence fertility are not fully understood.

In summary, the use of Vitex agnus-castus to support or treat infertility is primarily justified by tradition, with some suggestive but not definitive scientific evidence. More rigorous research is needed to firmly establish its efficacy and safety for this purpose.

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