Evidence supporting the use of: Bacillus (mixed)
For the health condition: Inflammatory Bowel Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacillus (mixed species) are spore-forming probiotic bacteria that have been studied for their potential benefits in gastrointestinal health, including Inflammatory Bowel Disorders (IBD) such as Crohn’s disease and ulcerative colitis. While there is a long history of probiotic use for gut health, the use of Bacillus species specifically for IBD is based primarily on emerging scientific research rather than traditional use.

Several small clinical trials and preclinical studies suggest possible benefits. Bacillus coagulans has shown some promise in randomized, placebo-controlled trials for improving symptoms in patients with irritable bowel syndrome (IBS), but data in IBD are limited. Some animal studies and pilot human trials report reduced inflammation and improved gut barrier function with Bacillus subtilis and Bacillus coagulans supplementation. The proposed mechanisms include modulation of the immune response, competitive inhibition of pathogenic bacteria, and enhancement of mucosal barrier integrity.

However, compared to better-studied probiotics like Lactobacillus and Bifidobacterium species, the evidence base for Bacillus (especially as mixed species) in IBD remains limited and of low quality. Most studies are small, short-term, and sometimes industry-funded. Systematic reviews conclude that while Bacillus-based probiotics appear safe, robust evidence supporting their efficacy in IBD is lacking and more large, well-designed clinical trials are needed. Therefore, current use is justified by preliminary scientific research rather than tradition, with overall evidence rated as weak to moderate (2/5).

More about Bacillus (mixed)
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
akkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fiber

Products containing Bacillus (mixed)

We currently have no products on Vitabase that contain this ingredient.