Evidence supporting the use of: Basidiomycota
For the health condition: Inflammatory Bowel Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Basidiomycota, a phylum of fungi that includes medicinal mushrooms such as Ganoderma lucidum (Reishi), Coriolus versicolor (Turkey tail), and Lentinula edodes (Shiitake), has been studied for its potential role in supporting or treating Inflammatory Bowel Disorders (IBD), including Crohn's disease and ulcerative colitis. Scientific interest is based primarily on the immune-modulating, anti-inflammatory, and antioxidant properties of polysaccharides, particularly beta-glucans, found in these fungi.

Preclinical studies in cell culture and animal models have demonstrated that extracts from certain Basidiomycota species can reduce inflammation, decrease oxidative stress, and modulate gut microbiota. For example, Ganoderma lucidum polysaccharides have shown to alleviate colitis symptoms in mice by reducing pro-inflammatory cytokines and restoring barrier function. Similarly, Coriolus versicolor extracts have exhibited immunomodulatory effects relevant to IBD pathology.

However, human clinical evidence remains limited and generally of low quality. A few small pilot trials and case reports suggest some improvement in symptoms or biomarkers, but large-scale, well-controlled clinical studies are lacking. Most available data come from preclinical research, making current scientific validation suggestive but preliminary. Therefore, while use of Basidiomycota in IBD management is partially supported by scientific findings, the evidence is not strong enough for firm clinical recommendations at this time.

More about Basidiomycota
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Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
akkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fiber

Products containing Basidiomycota

We currently have no products on Vitabase that contain this ingredient.