Evidence supporting the use of: Beta Hydroxybutyrate
For the health condition: Inflammatory Bowel Disorders

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Beta Hydroxybutyrate (BHB) is a ketone body produced during states of ketosis, such as fasting or ketogenic diets. Interest in BHB for inflammatory bowel disorders (IBD), such as Crohn’s disease and ulcerative colitis, is relatively recent and based primarily on preclinical studies. In animal models, BHB has demonstrated anti-inflammatory properties, including inhibition of the NLRP3 inflammasome, a key mediator of inflammatory responses implicated in IBD pathology (Youm et al., Nature Medicine, 2015). Additionally, ketone bodies like BHB may modulate gut microbiota and enhance the intestinal barrier, which are relevant mechanisms in IBD (Poff et al., Frontiers in Immunology, 2020). However, robust clinical evidence in human patients with IBD is lacking, and there are no established guidelines recommending BHB supplementation for IBD management. Most data come from mechanistic cell culture, animal models, and extrapolation from the effects of ketogenic diets. Thus, while there is scientific rationale and preliminary evidence for BHB’s anti-inflammatory effects, the clinical efficacy and safety of BHB supplementation in IBD patients remain to be established through high-quality clinical trials.

More about Beta Hydroxybutyrate
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
akkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fiber

Products containing Beta Hydroxybutyrate

We currently have no products on Vitabase that contain this ingredient.