Evidence supporting the use of: Celandine
For the health condition: Inflammatory Bowel Disorders
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Celandine (Chelidonium majus) has a long history of use in traditional European herbal medicine, primarily for liver and digestive disorders. Its use in supporting or treating Inflammatory Bowel Disorders (IBD), such as Crohn’s disease or ulcerative colitis, is mainly based on its historical application for general gastrointestinal complaints, including indigestion, biliary disorders, and cramps. There is limited direct evidence from scientific studies specifically evaluating celandine for IBD. Some laboratory and animal studies have shown that celandine extracts possess anti-inflammatory and antispasmodic properties, which may theoretically offer some benefit in inflammatory gut conditions. However, robust clinical trials in humans with IBD are lacking.
Traditionally, celandine was used in various forms (e.g., infusions, tinctures) for its purported ability to relieve gastrointestinal discomfort. Its alkaloid content, including chelidonine, is thought to be responsible for these effects. Despite these traditional claims, modern scientific validation for its efficacy and safety in IBD remains insufficient. Moreover, celandine has been associated with potential hepatotoxicity, raising concerns about its use, especially for prolonged periods or in patients with pre-existing liver conditions. In summary, celandine’s use for IBD is primarily justified by traditional use, with only weak supporting evidence from preclinical studies and no solid clinical validation.
More about Celandine
More about Inflammatory Bowel Disorders
Other ingredients used for Inflammatory Bowel Disorders
2'-Fucosyllactoseakkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fiber