Evidence supporting the use of: Galactooligosaccharides
For the health condition: Inflammatory Bowel Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Galactooligosaccharides (GOS) are prebiotic fibers that are increasingly studied for their potential role in managing Inflammatory Bowel Disorders (IBD), including Crohn’s disease and ulcerative colitis. The rationale for their use is rooted in their ability to modulate the gut microbiota, encouraging the growth of beneficial bacteria such as Bifidobacteria and Lactobacilli, which are often depleted in IBD patients.
Several small-scale clinical trials and animal studies have investigated GOS supplementation in IBD. Some studies report that GOS can improve gut barrier function, reduce intestinal inflammation, and increase the production of short-chain fatty acids like butyrate, which have anti-inflammatory properties. For example, a pilot study in ulcerative colitis patients suggested that GOS supplementation was associated with increased Bifidobacteria and some improvement in symptoms. However, these studies are generally limited in size and duration, and results are often inconsistent.
Systematic reviews conclude that while GOS and other prebiotics show promise, the evidence is not yet robust enough to recommend routine use for all IBD patients. More large-scale, well-controlled trials are needed to confirm clinical efficacy. Therefore, the use of GOS for IBD is supported by emerging but still preliminary scientific evidence, rather than by historical or traditional use.
More about galactooligosaccharides
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Other ingredients used for Inflammatory Bowel Disorders
2'-Fucosyllactose7,14-Hydroxy-Docosapentaenoic Acid
Acemannan
Akkermansia muciniphila
Algae
algal oil
Aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
andrographolide
anthocyanidins
anthocyanins
apigenin
apocynin
arabinoxylan
arctiin
astragalin
avocado
Bacillus
bacillus clausii
Bacillus licheniformis
bacillus subtilis
bacteria
barberry
barley
Basidiomycota
bentonite
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bioflavonoids
Boswellia
Boswellic Acid
Brassica
butternut
butyrate triglyceride
butyric acid
cannabidiol
casticin
cat's claw
celandine
chamomile
chirata
cichoric acid
citrus pectin
Coptis chinensis
cruciferous
curcumin
dandelion
DHA (docosahexaenoic acid)
eicosapentaenoic acid
ellagitannin
Enterococcus
EPA (eicosapentaenoic acid)
fiber
fish oil
flavans
flaxseed
Frangula
fructooligosaccharides (FOS)
fucoidan
galactooligosaccharides
Glucosinolates
Glutathione
Glycomacropeptides
Glycosphingolipids
Glycyrrhetinic acid
Humic acid
inulin
isomalto-oligosaccharide
Kaempferol
L-glutamine
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus brevis
Lactobacillus casei
Lactobacillus crispatus
Lactobacillus delbrueckii
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus johnsonii
Lactobacillus kefiranofaciens
Lactobacillus kefiri
Lactobacillus lactis
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus sakei
Lactobacillus salivarius
Lactococcus casei
Lactococcus lactis
Lactococcus rhamnosus
Legume protein
licorice root
luteolin
Marshmallow
Myrosinase
Myrrh
N-acetyl-cysteine (NAC)
N-acetyl-glucosamine
Neoandrographolides
nicotinamide riboside
Oligosaccharides
omega-3 fatty acids
Palmitoylethanolamide (PEA)
Pediococcus acidilactici
Pediococcus pentosaceus
Peppermint
phlorotannins
Piperine
polysaccharides
polyunsaturated fat
proanthocyanidins
probiotics
procyanidin
Propionibacterium freudenreichii
psyllium
punarnava
punicalagins
reishi mushroom
rosmarinic acid
Rubia cordifolia
Saccharomyces boulardii
shiitake mushroom
Slippery Elm
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
Sulfated polysaccharide
Sulforaphane
Swertia
Taraxasterol
Trametes
tributyrin
Tumerone
turmeric
Urolithin A
vitamin C
vitamin D
vitamin D3
Xylanase
xylooligosaccharides
Zinc
Other health conditions supported by galactooligosaccharides
Allergies (food)Allergies (respiratory)
Antibiotics (side effects of)
Autoimmune Disorders
Cholesterol (high)
Colds (prevention)
Constipation (adults)
Constipation (children)
Diabetes
Diarrhea
Digestion (poor)
Inflammation
Inflammatory Bowel Disorders
Irritable Bowel Syndrome
Lactose Intolerance
Leaky Gut Syndrome
Metabolic Syndrome
Stress