Evidence supporting the use of: Humic acid
For the health condition: Inflammatory Bowel Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Humic acid, a major component of humic substances found in soil and peat, has gained attention for its potential benefits in gastrointestinal health, including Inflammatory Bowel Disorders (IBD) such as Crohn's disease and ulcerative colitis. The scientific evidence supporting its use is limited but promising, warranting a moderate rating of 2 out of 5. Preclinical studies, mostly in animal models, suggest that humic acid has anti-inflammatory, antioxidant, and immunomodulatory effects. For instance, several rodent studies have demonstrated that oral administration of humic acid can reduce colonic inflammation, decrease pro-inflammatory cytokine levels, and improve histological features of colitis. The proposed mechanisms for these effects include modulation of gut microbiota, strengthening of the intestinal barrier, and inhibition of inflammatory mediators like TNF-alpha and interleukins. However, rigorous clinical trials in humans are scarce. Only a handful of small pilot studies or case reports have evaluated humic acid in IBD patients, with some reporting symptomatic improvement and reduced markers of inflammation. Due to the lack of large, well-controlled human studies, humic acid is not yet an established or mainstream therapy for IBD. In summary, while there is some scientific rationale and preliminary evidence for the use of humic acid in IBD, it remains investigational and should not replace evidence-based treatments. Further research, especially robust clinical trials, is needed to determine its efficacy and safety in this context.

More about Humic acid
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Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
akkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fiber

Products containing Humic acid

We currently have no products on Vitabase that contain this ingredient.