Evidence supporting the use of: Myrosinase
For the health condition: Inflammatory Bowel Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Myrosinase is an enzyme found in cruciferous vegetables (like broccoli and Brussels sprouts) that catalyzes the hydrolysis of glucosinolates to form biologically active isothiocyanates, such as sulforaphane. Research interest has focused on the potential anti-inflammatory and antioxidant effects of these isothiocyanates, particularly sulforaphane, in the context of inflammatory bowel disorders (IBD) such as Crohn’s disease and ulcerative colitis. Preclinical studies in animal models have demonstrated that sulforaphane can reduce markers of inflammation, oxidative stress, and tissue damage in the gut. Myrosinase is sometimes added to supplements to ensure conversion of glucoraphanin (the precursor) to sulforaphane in the human digestive system, since gut microbiota alone may not provide sufficient enzymatic activity. However, direct evidence from human clinical trials specifically evaluating myrosinase—or myrosinase-enhanced preparations—for IBD is limited. Most of the available research has focused on sulforaphane-rich extracts or cruciferous vegetable intake rather than isolated myrosinase supplementation. While mechanistic and animal studies suggest a potential benefit, robust human data are lacking. Thus, the scientific rationale exists and is supported by preclinical research, but clinical evidence remains preliminary, meriting a moderate-low evidence rating.
More about Myrosinase
More about Inflammatory Bowel Disorders
Other ingredients used for Inflammatory Bowel Disorders
2'-Fucosyllactose7,14-Hydroxy-Docosapentaenoic Acid
Acemannan
Akkermansia muciniphila
Algae
algal oil
Aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
andrographolide
anthocyanidins
anthocyanins
apigenin
apocynin
arabinoxylan
arctiin
astragalin
avocado
Bacillus
bacillus clausii
Bacillus licheniformis
bacillus subtilis
bacteria
barberry
barley
Basidiomycota
bentonite
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bioflavonoids
Boswellia
Boswellic Acid
Brassica
butternut
butyrate triglyceride
butyric acid
cannabidiol
casticin
cat's claw
celandine
chamomile
chirata
cichoric acid
citrus pectin
Coptis chinensis
cruciferous
curcumin
dandelion
DHA (docosahexaenoic acid)
eicosapentaenoic acid
ellagitannin
Enterococcus
EPA (eicosapentaenoic acid)
fiber
fish oil
flavans
flaxseed
Frangula
fructooligosaccharides (FOS)
fucoidan
galactooligosaccharides
Glucosinolates
Glutathione
Glycomacropeptides
Glycosphingolipids
Glycyrrhetinic acid
Humic acid
inulin
isomalto-oligosaccharide
Kaempferol
L-glutamine
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus brevis
Lactobacillus casei
Lactobacillus crispatus
Lactobacillus delbrueckii
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus johnsonii
Lactobacillus kefiranofaciens
Lactobacillus kefiri
Lactobacillus lactis
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus sakei
Lactobacillus salivarius
Lactococcus casei
Lactococcus lactis
Lactococcus rhamnosus
Legume protein
licorice root
luteolin
Marshmallow
Myrosinase
Myrrh
N-acetyl-cysteine (NAC)
N-acetyl-glucosamine
Neoandrographolides
nicotinamide riboside
Oligosaccharides
omega-3 fatty acids
Palmitoylethanolamide (PEA)
Pediococcus acidilactici
Pediococcus pentosaceus
Peppermint
phlorotannins
Piperine
polysaccharides
polyunsaturated fat
proanthocyanidins
probiotics
procyanidin
Propionibacterium freudenreichii
psyllium
punarnava
punicalagins
reishi mushroom
rosmarinic acid
Rubia cordifolia
Saccharomyces boulardii
shiitake mushroom
Slippery Elm
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
Sulfated polysaccharide
Sulforaphane
Swertia
Taraxasterol
Trametes
tributyrin
Tumerone
turmeric
Urolithin A
vitamin C
vitamin D
vitamin D3
Xylanase
xylooligosaccharides
Zinc
Other health conditions supported by Myrosinase
Cancer (natural therapy for)Cancer (prevention)
Inflammation
Inflammatory Bowel Disorders
Liver Detoxification