Evidence supporting the use of: Phyllanthus fraternus
For the health condition: Inflammatory Bowel Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phyllanthus fraternus, a species in the Phyllanthus genus, has been traditionally used in various systems of medicine in India and other parts of Asia for liver disorders, jaundice, and kidney ailments. Increasingly, it has also been investigated for its anti-inflammatory properties, which are of interest in the context of Inflammatory Bowel Disorders (IBD) such as Crohn’s disease and ulcerative colitis. Several preclinical studies have demonstrated that extracts of Phyllanthus fraternus possess significant antioxidant and anti-inflammatory activities. For example, animal studies have shown that its extracts can reduce markers of inflammation in chemically induced models of colitis, likely through inhibition of pro-inflammatory cytokines and free radicals. These effects are attributed to the presence of bioactive compounds such as lignans, flavonoids, and tannins. However, while these preclinical results are promising, clinical evidence in humans is lacking. There are no published randomized controlled trials or well-designed clinical studies evaluating the efficacy or safety of Phyllanthus fraternus specifically in patients with IBD. Thus, while there is a scientific rationale and some laboratory validation for its use in inflammatory conditions, the evidence for its use in IBD is currently limited to animal models and in vitro studies. More rigorous human studies are needed before it can be recommended for treating IBD.

More about Phyllanthus fraternus
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Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
akkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fiber

Products containing Phyllanthus fraternus

We currently have no products on Vitabase that contain this ingredient.