Evidence supporting the use of: Polyphenol (unspecified)
For the health condition: Inflammatory Bowel Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols are a diverse group of naturally occurring compounds found in plants, including fruits, vegetables, tea, and wine. Their use in supporting or treating Inflammatory Bowel Disorders (IBD), such as Crohn’s disease and ulcerative colitis, is primarily justified by growing scientific evidence rather than long-standing tradition. Preclinical studies (in vitro and animal models) have consistently demonstrated that polyphenols, including flavonoids, phenolic acids, and stilbenes, possess antioxidant, anti-inflammatory, and immunomodulatory properties. These mechanisms are relevant to IBD pathophysiology, which involves chronic intestinal inflammation and oxidative stress. Several small-scale human clinical trials have investigated specific polyphenols, such as curcumin (from turmeric), resveratrol, and epigallocatechin gallate (from green tea), with some reporting improvements in clinical symptoms, inflammatory markers, and quality of life in patients with IBD. However, evidence is often limited by small sample sizes, short duration, variability in polyphenol types and dosages, and the use of polyphenol-rich foods or extracts rather than isolated compounds. Systematic reviews and meta-analyses suggest potential benefit, but emphasize the need for larger, well-controlled trials. Overall, the use of polyphenols in IBD is supported by mechanistic rationale and preliminary clinical data, but conclusive evidence is lacking. Polyphenols may be considered as adjuncts, not replacements, for standard medical therapy. Further research is warranted to clarify their efficacy, optimal types, and dosing regimens in IBD management.

More about Polyphenol (unspecified)
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
akkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fiber

Products containing Polyphenol (unspecified)

We currently have no products on Vitabase that contain this ingredient.