Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rubia cordifolia, commonly known as Indian Madder or Manjistha, has a long-standing history of use in traditional Ayurvedic and Chinese medicine for a variety of ailments, including inflammatory conditions and disorders of the gastrointestinal tract. In Ayurveda, Manjistha is considered to have detoxifying and anti-inflammatory properties and is sometimes recommended for conditions involving chronic inflammation, such as Inflammatory Bowel Disease (IBD), though its use is generally more common for skin diseases, blood purification, and liver support. The rationale for its use in IBD stems from its described ability to "cool" and cleanse the blood, and to reduce inflammation, which are considered beneficial actions in traditional frameworks for managing bowel inflammation.

Scientific studies exploring Rubia cordifolia specifically for IBD are limited. Some preclinical studies have demonstrated anti-inflammatory, antioxidant, and immunomodulatory properties of its extracts, and a few animal studies have shown reduction in markers of inflammation in models of colitis. However, robust clinical trials in humans with IBD are lacking, and no consensus exists in modern medicine regarding its efficacy for this condition. Thus, while there is a traditional basis for its use, the scientific evidence remains preliminary and not definitive. For individuals with IBD, use of Rubia cordifolia should be approached with caution and under professional supervision, as more research is needed to clarify its safety and efficacy.

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