Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin D3 is used to support or treat Inflammatory Bowel Disorders (IBD), such as Crohn’s disease and ulcerative colitis, based on a growing body of scientific evidence. Epidemiological studies have shown that patients with IBD are more likely to have vitamin D deficiency compared to the general population. This deficiency may be due to malabsorption, reduced sunlight exposure, or chronic inflammation. Vitamin D plays an immunomodulatory role, influencing both innate and adaptive immune responses, which are central to the pathogenesis of IBD. Several observational studies suggest that low vitamin D levels are associated with increased disease activity, higher risk of relapse, and poorer quality of life in IBD patients.

Interventional studies, including randomized controlled trials, have evaluated vitamin D supplementation in IBD. Some have reported that supplementation can reduce disease activity scores, lower inflammatory biomarkers (such as C-reactive protein), and decrease the risk of relapse, especially in patients with established deficiency. However, results are mixed, and not all studies show significant clinical improvement. Meta-analyses generally conclude that while vitamin D supplementation is safe and may provide modest benefits, more large-scale, high-quality trials are needed to confirm its efficacy as a primary or adjunctive therapy for IBD. Overall, scientific evidence supports monitoring and correcting vitamin D deficiency in IBD patients, and supplementation is recommended as part of comprehensive disease management.

More about vitamin D3
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

Other health conditions supported by vitamin D3

Products containing vitamin D3

Designs For Health Acnutrol™ capsules
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Pure Encapsulations Vitamin D3 250 mcg 10,000 IU
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Metagenics Wellness Essentials Men's Vitality Daily Packs
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Pure Encapsulations Women's Nutrients
Designs For Health Women's Twice Daily Essential Packets