Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Xylooligosaccharides (XOS) are prebiotic fibers derived from plant sources such as corn cobs and bamboo. Their primary mechanism of action is the selective stimulation of beneficial gut bacteria, particularly Bifidobacterium and Lactobacillus species. Emerging scientific research suggests that modulation of the gut microbiota through prebiotics like XOS may play a supportive role in managing Inflammatory Bowel Disorders (IBD), including Crohn’s disease and ulcerative colitis. Several animal studies and a limited number of small human trials have demonstrated that XOS supplementation can improve intestinal barrier integrity, reduce markers of inflammation, and shift the gut microbiome towards a more anti-inflammatory profile. For example, studies in rodent models of colitis have shown reductions in pro-inflammatory cytokines and improvements in disease severity scores following XOS administration. However, human clinical data remain sparse and are typically limited to surrogate markers rather than direct measures of disease remission or flare prevention. While prebiotics in general have a plausible mechanism and some supportive evidence for gut health, direct evidence that XOS alone can treat or significantly ameliorate IBD in humans is currently modest. Thus, while there is a scientific rationale and preliminary validation for the use of XOS as an adjunctive intervention, further well-powered, controlled clinical trials are needed to fully establish efficacy and optimal usage protocols in IBD patients.

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Other ingredients used for Inflammatory Bowel Disorders

Other health conditions supported by xylooligosaccharides

Products containing xylooligosaccharides

Vitabase 7 Day Colon Cleanse
Pure Encapsulations Poly-Prebiotic Powder
Designs For Health PrebioMed™ XOS
Vitabase Probiotic Blend
Pure Encapsulations PureLean® Fiber