Evidence supporting the use of: Boneset
For the health condition: Influenza

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Boneset (Eupatorium perfoliatum) has a long history of use in North American traditional medicine, especially among Native American groups and 19th-century herbalists, for treating feverish illnesses such as influenza ("the flu"). The plant was commonly used during influenza outbreaks, earning its name because it was believed to relieve the "breakbone fever" (severe bone pain) associated with the flu. Traditional preparations include teas and tinctures made from the aerial parts of the plant, which were reputed to reduce fever, promote sweating, and ease body aches.

Modern scientific validation for boneset's effectiveness against influenza is limited. Laboratory studies have shown some immunomodulatory, anti-inflammatory, and mild antiviral effects from certain compounds in boneset, such as polysaccharides and flavonoids. However, robust clinical trials in humans are lacking, and there is insufficient evidence to confirm safety or efficacy for influenza treatment by contemporary medical standards. Most available data are anecdotal or based on historical usage.

In summary, while boneset’s use for influenza is well-supported by tradition and historical reports, there is not enough scientific evidence to recommend it confidently for treating the flu today. Caution is also advised, as improper preparation or high doses may cause adverse effects such as nausea or liver toxicity.

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