Evidence supporting the use of: Cordyceps
For the health condition: Influenza

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cordyceps, a genus of parasitic fungi used in traditional Chinese medicine, has garnered interest for its potential antiviral and immunomodulatory properties. The use of Cordyceps to support or treat influenza is justified primarily by emerging scientific evidence, although the strength of this evidence is still limited and mostly preclinical.

Several in vitro and animal studies have investigated the effects of Cordyceps extracts against influenza viruses. For instance, research has shown that Cordyceps militaris and Cordyceps sinensis extracts can inhibit the replication of influenza A virus in cell cultures and mice models. Proposed mechanisms include the modulation of immune responses, such as increasing the production of interferons and enhancing the activity of natural killer (NK) cells, as well as direct inhibition of viral replication.

Additionally, Cordyceps contains bioactive compounds (e.g., cordycepin, polysaccharides) with demonstrated antioxidant and anti-inflammatory effects, which could theoretically mitigate some symptoms and complications of influenza infection. However, there are very few well-designed human clinical trials assessing the efficacy of Cordyceps specifically for influenza, and most existing evidence remains preliminary or indirect.

In summary, while Cordyceps has a long history of traditional use for respiratory health and immune support, its specific application for influenza is currently supported by modest scientific evidence from laboratory and animal studies. More rigorous human clinical research is needed before Cordyceps can be recommended as an evidence-based treatment or adjunct for influenza.

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