Evidence supporting the use of: EGCG
For the health condition: Influenza

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Epigallocatechin gallate (EGCG), a major polyphenol found in green tea, has been investigated for its potential antiviral effects against influenza viruses. Several in vitro studies have demonstrated that EGCG can inhibit the entry and replication of influenza A and B viruses by interfering with viral hemagglutinin binding to host cells and suppressing viral RNA synthesis. Additionally, EGCG has been shown to have immunomodulatory and antioxidant properties that may contribute to its antiviral activity. However, while the laboratory evidence is promising, there is a lack of robust clinical trials in humans demonstrating that EGCG supplementation effectively prevents or treats influenza infection. Most evidence to date is preclinical, based on cell culture and animal models, with only limited and inconclusive data from small-scale human studies. Traditional use of green tea for general health and immunity exists, but its specific use for influenza is not well-documented historically. In summary, EGCG's use for influenza is primarily supported by preclinical scientific evidence, warranting further investigation, but at present, the clinical evidence remains limited.

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Products containing EGCG

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