Evidence supporting the use of: Fritillaria (unspecified)
For the health condition: Influenza

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Fritillaria species, particularly Fritillaria cirrhosa and Fritillaria thunbergii, are widely used in Traditional Chinese Medicine (TCM) for their purported expectorant and antitussive properties. Their bulbs, known as "Chuan Bei Mu" or "Zhe Bei Mu", are commonly included in herbal formulas intended to relieve coughs and clear phlegm, symptoms frequently associated with respiratory infections like influenza. Historical TCM texts mention their use for "wind-heat" or "phlegm-heat" conditions, which may overlap symptomatically with influenza.

The scientific evidence directly supporting Fritillaria for the treatment or prevention of influenza is limited. Some in vitro studies indicate that alkaloids in Fritillaria have anti-inflammatory and antitussive effects, and there are animal studies showing cough-suppressant activity. However, robust clinical trials assessing efficacy for influenza in humans are lacking. Most modern usage is based on traditional practice and symptom management rather than demonstrated antiviral activity against influenza viruses. Systematic reviews and pharmacopeias recognize the herb for cough and respiratory complaints but do not establish it as a primary treatment for influenza.

In summary, the use of Fritillaria against influenza is primarily justified by longstanding traditional practice, with only weak supportive evidence that is mostly limited to its symptom-relieving properties rather than antiviral action.

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