Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ganoderma, commonly known as Reishi mushroom (Ganoderma lucidum), has a long history of use in traditional Asian medicine for promoting health and longevity, including the prevention and treatment of respiratory infections like influenza. However, in recent years, several scientific studies have explored its potential antiviral and immunomodulatory effects. Preclinical research has demonstrated that extracts from Ganoderma lucidum can inhibit the replication of influenza viruses in vitro and modulate immune responses, potentially reducing the severity of influenza infection. These effects are thought to be due to triterpenoids and polysaccharides found in the mushroom, which have shown antiviral activity and the ability to enhance host immune defense mechanisms.

Despite promising laboratory and animal data, high-quality human clinical trials specifically investigating Ganoderma’s efficacy against influenza are limited. Most existing studies are preliminary, and there is a lack of large-scale, randomized controlled trials. Thus, while there is some scientific basis for its use as an adjunctive therapy or preventive measure against influenza, the evidence remains weak to moderate. It should not be considered a replacement for standard antiviral treatments or vaccination, but may be of interest for those seeking complementary approaches. More robust clinical research is needed to confirm its effectiveness and safety in the context of influenza in humans.

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