Evidence supporting the use of: Lactobacillus casei
For the health condition: Influenza

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus casei is a probiotic bacterium commonly found in the human gut and used in various fermented dairy products. Its use in supporting or treating influenza is primarily based on emerging scientific evidence, rather than tradition or longstanding clinical practice. Several animal and human studies suggest that L. casei may help modulate the immune system, potentially enhancing the body's response to viral infections, including influenza. For example, some preclinical studies have shown that oral administration of L. casei in mice can increase the production of influenza-specific antibodies and stimulate natural killer (NK) cell activity, which are both important for viral clearance. A limited number of small-scale human clinical trials have reported that consumption of L. casei-containing probiotics may slightly reduce the incidence, duration, or severity of upper respiratory tract infections, including influenza-like illness, in certain populations such as children and the elderly. However, these effects are modest, and results are not always consistent across studies. The exact mechanisms are still being explored, but they are thought to involve modulation of gut-associated lymphoid tissue and systemic immune responses. Overall, while there is some scientific support for the use of L. casei in enhancing immune responses to influenza, the evidence is not robust or conclusive, and it should not replace vaccination or antiviral therapies for influenza prevention or treatment.

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