Evidence supporting the use of: Osthole
For the health condition: Influenza

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Osthole is a natural coumarin compound found in several medicinal plants, notably Cnidium monnieri. Its use in the context of influenza is supported by some preclinical scientific studies, rather than traditional usage. In vitro and animal studies have suggested that osthole possesses antiviral activity, including effects against influenza viruses. For example, research published in peer-reviewed journals indicates that osthole can inhibit the replication of influenza A virus in cell cultures, potentially by interfering with the viral life cycle or modulating host immune responses. Additionally, osthole has documented anti-inflammatory properties, which may help mitigate the excessive inflammatory response associated with severe influenza infections.

However, evidence is currently limited to laboratory and animal studies; there are no robust clinical trials in humans demonstrating efficacy or safety for influenza prevention or treatment. Osthole is not a standard or widely-recommended treatment for influenza in modern medicine, nor is it typically cited in traditional medicine specifically for influenza. Thus, while there is some scientific validation at the preclinical level, the overall quality and quantity of evidence remain low (rated 2/5), and further research—including well-designed human clinical trials—is needed before osthole could be recommended for influenza management.

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Products containing Osthole

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