Evidence supporting the use of: Premna
For the health condition: Influenza

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Premna species, such as Premna serratifolia, are used in various traditional medicine systems, particularly in Ayurvedic and Southeast Asian herbal practices, to manage fever, respiratory ailments, and symptoms commonly associated with influenza. Historical texts and ethnobotanical surveys document the use of Premna leaves and roots in decoctions or infusions aimed at reducing fever and alleviating cough and cold symptoms. The rationale for its use stems from its reputed antipyretic, anti-inflammatory, and antimicrobial properties, as described in traditional medical literature.

However, the direct scientific evidence supporting Premna's efficacy specifically against influenza viruses in humans is limited. Some in vitro studies have identified bioactive compounds in Premna (such as flavonoids, sterols, and diterpenoids) with general antimicrobial and anti-inflammatory activity, and a few animal model studies suggest potential immunomodulatory effects. Despite these findings, there is a lack of robust clinical trials or direct antiviral studies confirming its effectiveness for influenza treatment in humans.

In summary, while Premna's use for influenza is well-established in traditional medicine, scientific validation is limited and does not yet meet rigorous evidence standards. Its use remains primarily justified by traditional practice, with moderate evidence from preliminary pharmacological research but lacking high-quality clinical data.

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