Evidence supporting the use of: Reishi mushroom
For the health condition: Influenza

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has a long history of use in traditional Chinese medicine (TCM), where it is valued for its purported immune-modulating and antiviral properties. Traditionally, reishi has been used to strengthen the body's resistance to illness, support longevity, and improve vitality, rather than to treat acute infections like influenza directly. However, its general use as a "tonic" for the immune system has led to its application in supporting the body during flu season or when exposed to respiratory infections.

From a scientific perspective, there is some preliminary laboratory (in vitro) and animal research suggesting that compounds found in reishi, such as polysaccharides and triterpenoids, may enhance immune function and exhibit antiviral activity against certain viruses, including influenza strains. For example, studies have shown that reishi extracts can stimulate macrophage activity, increase production of interferons, and inhibit viral replication in cell cultures. However, high-quality clinical trials in humans specifically addressing the effectiveness of reishi for preventing or treating influenza are lacking.

Therefore, while there is a strong foundation in traditional use and some promising preclinical data, robust scientific validation in humans is insufficient at this time. Most support for reishi mushroom in the context of influenza relates to its overall reputation for immune support rather than direct, proven antiviral effects against the influenza virus.

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